Developmental biology of the leech Helobdella

• Autores: David A. Weisblat, Dian-Han Kuo
• Localización: International journal of developmental biology, ISSN 0214-6282, Vol. 58, Nº. 6-8, 2014 (Ejemplar dedicado a: Spiralian model systems), págs. 429-443
• Idioma: inglés
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• Resumen

  • Glossiphoniid leeches of the genus Helobdella provide experimentally tractable models for studies in evolutionary developmental biology (Evo-Devo). Here, after a brief rationale, we will summarize our current understanding of Helobdella development and highlight the near term prospects for future investigations, with respect to the issues of: D quadrant specification; the transition from spiral to bilaterally symmetric cleavage; segmentation, and the connections between segmental and non-segmental tissues; modifications of BMP signaling in dorsoventral patterning and the O-P equivalence group; germ line specification and genome rearrangements. The goal of this contribution is to serve as a summary of, and guide to, published work.