La inmugenética en el diagnóstico de las enfermedades postvacunales del SNC

• Autores: Massimo G. Montinari, Biagio Favoino, Angela Roberto
• Localización: Natura Medicatrix: Revista médica para el estudio y difusión de las medicinas alternativas, ISSN 0212-9078, Nº. 46-47 (Primavera - Verano), 1997, págs. 42-43
• Idioma: español
• Títulos paralelos:
  • Diagnostic roleofimmunogenetics in post-vaccine diseases of the cns: Preliminary results
• Enlaces
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• Resumen

  • We report of 30 patients with post-vaccine diseases of CNS and other organs who presented with the initial symptoms at the time of or immediately after vaccines. All patients were tested for Berpes virus (igG and IgM) and tissue typing (HLA A, B, C, HLA DR-DQ) to study the relationship between the development of post-vaccine CNS diseases and those antigens trying to show that an immunogenetic substrate (autoimmune type) is involved in demyelination processes. The comparison of our patients with normal Italian controls showed an increased presence of HLA A3 and DR-7 antigens in the former group. The occurrence of A3 and/or DR7 was observed in 22/30 patients (73.3%).