Microwave-Assisted Carbonyl Chemistry for the Undergraduate Laboratory

• Autores: S. Shaun Murphree, C. Oliver Kappe
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 86, Nº. 2 (February), 2009, págs. 227-229
• Idioma: inglés
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• Resumen

  • An instructional laboratory module suitable for a second- or third-year organic chemistry curriculum has been developed using microwave-assisted synthetic techniques. The module, which contains six discrete experiments, explores various aspects of carbonyl chemistry. Reaction times range from 3 minutes to 1 hour (two steps), and yields are consistently high (78–99%). Starting materials are inexpensive and readily available, and straightforward workup and purification (via extraction or recrystallization) provides products of acceptable purity without the need for chromatography.