Use of Chiral Oxazolidinones for a Multi-Step Synthetic Laboratory Module

• Autores: Matthew P. Betush, S. Shaun Murphree
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 86, Nº 1 (January), 2009, págs. 91-93
• Idioma: inglés
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• Resumen

  • Chiral oxazolidinone chemistry is used as a framework for an advanced multi-step synthesis lab. The cost-effective and robust preparation of chiral starting materials is presented, as well as the use of chiral auxiliaries in a synthesis scheme that is appropriate for students currently in the second semester of the organic sequence.