Resumen de On the Use of "Green" Metrics in the Undergraduate Organic Chemistry Lecture and Lab To Assess the Mass Efficiency of Organic Reactions.
John Andraos, Murtuzaali Sayed
This article describes a novel approach to evaluate the complete reaction mass efficiency (RME) and raw material cost (RMC) of any chemical transformation through the implementation of an Excel spreadsheet in a tax-form style and an easy graphical representation of the results. The complete equation for evaluating RME is presented. Students and their lab instructors will be able to see at once the material performance of their laboratory reaction and evaluate critically which of the four parameters (reaction yield, atom economy, stoichiometric factor, and material recovery parameter) needs further optimization to bring about a �greener� synthesis plan. The effect of material recovery options on RME and RMC are also given. The methodology is applied to a wide variety of organic reaction types and key trends in the material efficiency performances are summarized.
