The GC MS Observation of Intermediates in a Stepwise Grignard Addition Reaction.

• Autores: Devin Latimer
• Localización: Journal of chemical education, ISSN 0021-9584, Vol. 84, Nº 4, 2007, págs. 699-701
• Idioma: inglés
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• Resumen

  • This article describes a three-hour laboratory experiment for the third-year organic chemistry lab whereby the stable organic intermediates and final product of the Grignard addition of 3 equivalents of phenylmagnesium bromide to diethyl carbonate are observed. A 1-mL aliquot is removed from the reaction at the midpoint of addition and subjected to GC�MS analysis. An interesting mass spectral exercise shows the presence of the intermediates ethyl benzoate and benzophenone as well as the product triphenylmethanol.