Resumen de Comparative trial between the use of amoxicillin and amoxicillin clavulanate in the removal of third molars
Fernando Iglesias Martin, Alberto García-Perla García, Rosa María Yáñez Vico, Elena Aced Jiménez, Esther Arjona Gerveno, Juan David González Padilla, José Luis Gutiérrez Pérez, Daniel Torres Lagares
Objectives: The purpose of this study was to compare the use of amoxicillin (1g) vs amoxicillin and clavulanate (875/125mg) after extraction of retained third molars for prevention of infectious complications.
Study Design: The study involved 546 patients attending for removal a retained third molar and divided in to two groups: Group 1 - amoxicillin and clavunate (875/125mg) group (n=257) and Group 2 - amoxicillin (1g) group (n=289). All patients were recalled for investigating the possibility of infection, presence of diarrhea and further analgesic intake.
Results: From a total of 546 patients, the frequency of infection was 1.4%, without no statistically differences be - tween the two groups. Group 1 showed statistically higher presence of patients with gastrointestinal complications ( p>0.05).
In 546 patients, 2.7% of patients reported severe pain that would not relieve with medication.
Conclusions: The results of our study show that the use of amoxicillin (1g) and amoxicillin and clavunate (875/125mg) is similar efficacious in preventing infection after retained third molar extraction but amoxicillin and clavunate (875/125mg) produces more gastrointestinal discomfort.
