Priming and activation of NADPH oxidases in plants and animals

• Autores: Johnathan Canton, Sergio Grinstein
• Localización: Trends in immunology, ISSN 1471-4906, Vol. 35, Nº. 9, 2014, págs. 405-407
• Idioma: inglés
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• Resumen

  • In mammals, engagement of Toll-like receptors by microbe-associated molecular patterns enhances the responsiveness of NADPH oxidases. Two recent papers report a similar �priming� mechanism for the plant oxidase RbohD. Despite lacking structural homology, the functional parallels between plants and animals reveal that a common regulatory logic arose by convergent evolution.