Resumen de Hipersensibilidad a oxaliplatino. Pruebas cutáneas y protocolo de desensibilización
Susana Cortijo Cascajares, M. P. Goyache-Goñi, M.J. Vicario Zubizarreta, Mª Jesús Jiménez Cerezo, G. García Canto
Objectives: To evaluate the hypersensitiveness reactions to oxaliplatin (L-OHP), a chemotherapeutic agent used as a first-degree treatment for metastatic colorectal cancer; and the need for continuing with the treatment. To standardize the concentrations of L-OHP necessary for the making of cutaneous tests and the establishment of a desensitization protocol. Method: It was developed a study of patients treated with L-OHP that presented symptoms of anaphylaxis during the course of the treatment and it took place a revision of the available information in the literature. Results: The allergologic study was negative and a desensitization regime was successfully developed. Conclusions: The hypersensitiveness reactions to chemotherapeutic agents do not necessarily require the exclusion of such drugs from the treatment regime, because when a desensitization protocol is followed a safe administration of such drugs is achieved
