Resumen de Effects of Repeated Bouts of Supramaximal Exercise on Plasma Adiponectin, Interleukin-6, and Tumor Necrosis Factor-[alpha] Levels in Sedentary Men
Hakk Gökbel, Nilsel Okudan, Ibrahim Gül, Muaz Belviranli, Hasan S. Gergerlioglu, Mustafa K. BaSaral
The objective of the study was to determine the effects of repeated bouts of supramaximal exercise on plasma adiponectin, interleukin (IL)-6 and tumor necrosis factor (TNF)-[alpha] levels in sedentary men. Fourteen healthy, nonsmoking, and sedentary men aged between 18.4 and 21.4 years participated in the study. All the subjects performed 5 Wingate tests (WTs) with 75 g per kilogram body weight load with 2-minute intervals between the tests. Blood samples were collected at preexercise, immediately after, 15 and 60 minutes after the fifth WT. Serum and plasma samples were stored at -80°C until the time of analysis for myoglobin, adiponectin, IL-6, and TNF-[alpha]. Plasma adiponectin levels decreased, whereas IL-6 levels increased postexercise compared with that preexercise. The TNF-[alpha] levels were not changed with supramaximal exercise. In conclusion, repeated bouts of supramaximal exercise cause an inflammatory response in exercised muscle and increase in plasma IL-6 levels and decrease in adiponectin concentrations.
