According to the American Cancer Society, metastatic melanoma represents only 5% of all dermatology malignancies in the skin, but it is responsible for 80% of all deaths. Due to a delay in diagnosis, it is estimated that only 14% of patients survive 5 years after diagnosis.2 BRAF mutation has been reported in multiples types of cancer but there is currently no information on the prevalence of the BRAF mutation among Latin-Americans, especially in Mexican population. The most frequent mutation in this oncogen (BRAF V600) represents the 90% of cases, therefore the objective of the study is to determine the prevalence of the BRAF mutation among a sample of patients with melanoma from the Northeast of México and correlate it to clinical characteristics.
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