The intraoperative anaphylactic reaction risk is from 9 to 19% of all complications associated to anesthesia and the percentage of perioperative deaths due to anaphylactic shock is estimated between 5 and 7%. Reactions associated to latex are from the simple sensitization, without any clinical manifestation, to the allergy with anaphylactic shock. We present a case of a 38-year-old patient, without any pathologic antecedents of interest, that was programmed for cervical discectomy. Two hours after the anesthesia induction, the patient presented a case of desaturation measured by the pulsoximeter, bronchospasm, hypotension and tachycardia that partially reverted with a symptomatic treatment. It was observed an edema and a facial generalized erythema. The patient was taken to an Intensive Care Unit (ICU) where he was extubated at the immediate postoperative. He was discharged at 48 hours. 30 days after, the latex allergy test was carried out by means of cutaneous tests, prick test, obtaining a positive result, with the determination of the specific serum IgE (CAP-system) that was 6.39 KU/L (positive class 3). Others medication cutaneous tests used were negative. An anaphylactic reaction to latex was present in a patient that does not belong to the population at risk. Mainly, allergic reactions contribute, to the perioperative morbimortality; however, these are quite unfrequent manifestations. In spite of the difficulty of these reactions in becoming the first consideration for the anesthesiologist, we should always take them into consideration as a differential diagnose for this type of symptoms
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