Inmunoglobulinas intravenosas: Situación actual y propuestas de mejora

• Autores: Isabel Villar Fernández, P. Casajús Lagranja, A. Idoipe Tomás, Mª J. Agustín Ferrández, Pablo Palomo Palomo
• Localización: Atención Farmacéutica, ISSN 1139-7357, Vol. 7, Nº. 2, 2005, págs. 89-96
• Idioma: español
• Títulos paralelos:
  • Intravenous immunoglobulins: Current situation and proposals for improvement
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• Resumen

  • Objective: To evaluate unspecific intravenous immunoglobulins (IVIG) use in new patients to assess proposals for improvement. Method: Observational retrospective study during 2003. Data sources: clinical records (CR), pharmacotherapeutic files and prescription forms. Results: Out of 49 new patients, 37 authorized indications were recorded, 5 unauthorized and 7 unrecognized. Only one compassionate use was processed. Most frequent pathologies: ITP (40.8%), Guillain-Barre syndrome (12.2%) and post-BMT (10.2%). The department that prescribed the most was Hematology (55%), followed by Neurology and Pediatrics. The exact weight to calculate the dosage was recoverable only in half of the CR. Eight patients had an adverse reaction to IVIG. Conclusions: The degree of adherence to the authorized indications by the AEM is high, but the processing of compassionate uses is scarce. Proposals for improvement: a protocol revision, the diffusion of an internal guidebook, an update on the IVIG request form and a greater supervision from the Pharmacy Department