Evolución de la terapia antirretroviral en pacientes pediátricos VIH+

• Autores: E. Fernández Sánchez, Teresa Aznar Saliente, María Dolores Camacho Romera, Raul González Montero
• Localización: Atención Farmacéutica, ISSN 1139-7357, Vol. 2, Nº. 3, 2000, págs. 234-238
• Idioma: español
• Títulos paralelos:
  • The evolution of antiretroviral therapy in paediatric HIV+ patients
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• Resumen

  • Drug therapy for the human immunodeficiency virus (HIV) has changed considerably since the virus was identified in 1983. Therapy has evolved widely, from the use of monotherapy with AZT, to the association of two nucleoside analogues, until the present use of treatment combinations with three drugs: two nucleoside analogues plus a protease inhibitor as well as the use of quadruple therapy regimens. The aim of the study is to examine the evolution of the different combinations (monotherapy, bitherapy, tritherapy, tetratherapy) undergone in a selected sample of 13 pediatric HIV+ patients, between January 1996 and April 1999, considering disease progression and the possible toxicities that could arise