Resumen de Guidelines for the use of human immunoglobulin therapy in patients with primary immunodeficiencies in Latin America

A. Condino-Neto, B. T. Costa-Carvalho, Anete Sevciovic Grumach, L. Bezrodnik, M. Oleastro, L.E. Leiva, O. Porras, F.J. Espinosa-Rosales, J.L. Franco, R.U. Sorensen

• Antibodies are an essential component of the adaptative immune response and hold long-term memory of the immunological experiences throughout life. Antibody defects represent approximately half of the well-known primary immunodeficiencies requiring immunoglobulin replacement therapy. In this article, the authors review the current indications and therapeutic protocols in the Latin American environment. Immunoglobulin replacement therapy has been a safe procedure that induces dramatic positive changes in the clinical outcome of patients who carry antibody defects.