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Pregabalin in the treatment of inferior alveolar nerve paraesthesia following overfilling of endodontic sealer

  • Autores: Luis Oscar Alonso Ezpeleta, Pablo J. Martín, José López López, Lizett Castellanos Cosano, Jenifer Martín González, Juan J. Segura Egea
  • Localización: Journal of Clinical and Experimental Dentistry, ISSN-e 1989-5488, Vol. 6, Nº. 2 (abril), 2014, págs. 197-202
  • Idioma: inglés
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  • Resumen
    • A case of orofacial pain and inferior alveolar nerve (IAN) paraesthesia after extrusion of endodontic sealer within the mandibular canal treated with prednisone and pregabalin is described. A 36-year-old woman underwent root canal treatment of the mandibular second right premolar tooth. Post-operative panoramic radiograph revealed the presence of radiopaque canal sealer in the mandibular canal. Damage to IAN consecutive to extrusion of endodontic sealer was diagnosed. Non-surgical management was decided, including: 1 mg/kg/day prednisone 2 times/day, once-daily regimen, and 150 mg/day pregabalin, two doses per day, monitoring the progress with periodic follow-up visits. Six weeks after the incident the signs and symptoms were gone. The complete resolution of paraesthesia and the control of pain achieved suggest that a non-surgical approach, combining prednisone and the GABA analogue pregabalin, is a good option in the management of the IAN damage subsequent to endodontic sealer extrusion.


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