Microglia fuel the learning brain

• Autores: Thomas Blank, Tobias Goldmann, Marco Prinz
• Localización: Trends in immunology, ISSN 1471-4906, Vol. 35, Nº. 4, 2014, págs. 139-140
• Idioma: inglés
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• Resumen

  • Microglia, the brain resident macrophages, are first responders to any violation of central nervous system (CNS) homeostasis. A recent paper in Cell shows that the specific depletion of microglia causes deficits in learning-induced synaptic remodeling through paucity of the microglial neurotrophin brain-derived neurotrophic factor (BDNF).