Intravitreal bevacizumab syringes: Working protocol

• Autores: Antonio Monzón Moreno, M. Cameán Fernández, Vicente Merino Bohórquez, Gabriel Ramírez Soto
• Localización: European journal of clinical pharmacy: atención farmacéutica, ISSN 2385-409X, Vol. 15, Nº. 5, 2013, págs. 351-357
• Idioma: inglés
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• Resumen

  • The monoclonal antibody bevacizumab has been widely used using intravitreal syringes to treat age-related macular degeneration, even though it has not been officially approved for this indication (off-label use). On the other hand, ranibizumab has been officially approved for this indication. Bevacizumab could have other off-label uses (retinal vein occlusion, diabetic retinopathy, neovascular glaucoma, diabetic macular edema, etc). The objective of this paper is to review the off-label uses of bevacizumab and to present a proposal of the procedure for preparing intravitreal syringes of bevacizumab. Conclusions: some bibliographic documentation exists to support some of the off-label uses of bevacizumab, and we present a proposal of a procedure for preparing intravitreal syringes of bevacizumab with the best quality guarantees