Background: The purpose of this study was to examine the effects of combined exercise training on growth hormone (GH), insulinlike growth factor-1 (IGF-1), and metabolicsyndrome factors and determine whether the changes in GH and/or IGF-1 induced by exercise correlate to the metabolic-syndrome factors in healthy middle-aged women (50�65 years of age). Methods: The participants were randomly assigned into an aerobic-exercise training (walking + aerobics) group (AEG; n = 7), a combined-exercise training (walking + resistance training) group (CEG; n = 8), or a control group (CG; n = 7). Exercise sessions were performed 3 times per wk for 12 wk. The aerobic-exercise training consisted of walking and aerobics at 60�80% of heart-rate reserve, and the combined-exercise training consisted of walking and resistance exercise at 50�70% of 1-repetition maximum. Results: GH, percentage body fat, fasting glucose, systolic blood pressure, and waist circumference were significantly improved in CEG (p < .05). However, GH induced by exercise training showed no correlation with metabolic-syndrome factors. IGF-1 was not significantly increased in either AEG or CEG compared with CG. Conclusion: These results indicate that the combined-exercise training produced more enhancement of GH, body composition, and metabolic-syndrome factors than did aerobic-exercise training.
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