Medical Management of Inflammatory Bowel Disease in the Elderly: Balancing Safety and Efficacy

• Autores: Christina Y. Ha
• Localización: Clinics in geriatric medicine, ISSN 0749-0690, Vol. 30, Nº. 1, 2014, págs. 67-78
• Idioma: inglés
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• Resumen

  • The medical management of inflammatory bowel disease (IBD) in the older patient extends beyond luminal disease activity. Factors such as comorbidity, functional status, polypharmacy, and age-related changes in physical reserve and drug metabolism may affect therapeutic decision making. The older patient with IBD is more susceptible to disease-related complications and also to adverse events with therapy, particularly immunosuppression. Appropriate medication selection along with multidisciplinary care, factoring not only disease activity but also these age-related risk factors, may improve therapeutic outcomes and decrease adverse events to therapy.