Classification, epidemiology and therapies for testicular germ cell tumours

• Autores: Nikhil Vasdev, Andrew Moon, Andrew C. Thorpe
• Localización: International journal of developmental biology, ISSN 0214-6282, Vol. 57, Nº. 2-4, 2013 (Ejemplar dedicado a: Male germ dells in development and tumors), págs. 133-139
• Idioma: inglés
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• Resumen

  • Testicular germ cell tumours (TGCT) account for between 1% and 1.5% of male neoplasms and 5% of urological tumours in general. They are classified broadly into Seminoma, which resemble primordial germ cells (PGCs), and Non-Seminoma, which are either undifferentiated (embryonal carcinoma) or differentiated (exhibiting a degree of embryonic (teratoma) or extra-embryonic (yolk sac choriocarcinoma) patterning). We present the current details of the latest classification, epidemiology and treatment aspects of TGCT in the UK in our review.