Resumen de Vista Prospective Associations of B-Type Natriuretic Peptide With Markers of Left Ventricular Function in Individuals With and Without Type 2 Diabetes: An 8-year follow-up of the Hoorn
Maria H. Kroon, Katja Van Den Hurk, Marjan Alssema, Otto Kamp, Coen Stehouwer, Ronald Henry, Michaela Diamant, Frans Boomsma, Giel Nijpels, Walter Paulus, Jacqueline M. Dekker
To our knowledge, there has never been a population-based cohort study in which the relationship between BNP and changes in LV function (assessed by echocardiography) was examined. [...]the current study aimed to investigate prospective associations of BNP levels in a non-heart failure range with changes in markers of LV function and potential effect modification by type 2 diabetes. [...]our results demonstrate that higher BNP levels in a nonheart failure range were independently associated with increased LV mass and deteriorated LV diastolic function, but not LV systolic function over time, particularly in individuals with type 2 diabetes. [...]slightly elevated BNP levels should be interpreted differently in individuals with and without type 2 diabetes.
