Cyclical Variation in the Incidence of Childhood Type 1 Diabetes in Western Australia (1985-2010)

• Autores: Aveni Haynes, Max K. Bulsara, Carol Bower, Timothy W. Jones, Elizabeth A. Davis
• Localización: Diabetes care, ISSN-e 0149-5992, Vol. 35, Nº. 11, 2012, págs. 2300-2302
• Idioma: inglés
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• Resumen

  • To examine the incidence of childhood type 1 diabetes in Western Australia from 1985-2010. Incidence rates were calculated for children aged 0-14 years and were analyzed by calendar year, sex, and age at diagnosis. There were 1,873 cases, and the mean incidence was 18.1/100,000 person-years (95% CI: 17.5-19.2). The incidence increased by 2.3% a year (1.6-2.9%) with a sinusoidal 5-year cyclical variation of 14% (7-22%). The lowest rate of increase in incidence was observed in 0-4-year-olds. The cyclical pattern in incidence observed supports the role of environmental factors in childhood type 1 diabetes. [PUBLICATION ABSTRACT]