Resumen de Long-term Follow-up Study of Ingenol Mebutate Gel for the Treatment of Actinic Keratoses

Mark Lebwohl, Stephen Shumack, Linda Stein Gold

• Importance Ingenol mebutate is the active agent (a macrocyclic diterpene ester) in the sap of the plant Euphorbia peplus. This herb has been used as a traditional remedy for several different skin lesions, including skin cancers.

  Objective To assess 12-month recurrence rates and safety associated with ingenol mebutate gel treatment in patients who previously had achieved complete clearance of actinic keratoses.