End Points in Trials of Treatments for Skin Infections�Reply

• Autores: Philippe Prokocimer
• Localización: JAMA: the journal of the American Medical Association, ISSN 0098-7484, Vol. 309, Nº. 20, 2013, págs. 2091-2092
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • In Reply: Dr Spellberg raises the question of whether a cessation of lesion spread in ABSSSIs can be considered a cure of the disease. This issue was discussed by the Foundation for the National Institutes of Health working group on end points in ABSSSIs.1 The group's recommended end point is a 20% or greater decrease in lesion size at the 48- to 72-hour assessment rather than cessation of spread at this time point.