Saliva Polymerase Chain Reaction Assay for Detection and Follow-up of Herpesvirus Reactivation in Patients With Drug Reaction With Eosinophilia and Systemic Symptoms (DRESS)

• Autores: Vincent Descamps, Martine Avenel-Audran, Laurence Valeyrie-Allanore
• Localización: JAMA Dermatology, ISSN 2168-6068, Vol. 149, Nº. 5, 2013, págs. 565-569
• Idioma: inglés
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• Resumen

  • Importance Reactivations of human herpesviruses (HHVs) contribute to the development of drug reaction with eosinophilia and systemic symptoms (DRESS). Diagnosis of HHV reactivation is conventionally based on quantitative real-time polymerase chain reaction (PCR) analysis of blood samples, but these viruses are present in the oropharynx and are shed in saliva.