Falsification End Points for Observational Studies�Reply

• Autores: Anupam B. Jena, Vinay Prasad
• Localización: JAMA: the journal of the American Medical Association, ISSN 0098-7484, Vol. 309, Nº. 17, 2013 (Ejemplar dedicado a: Child Health), págs. 1769-1771
• Idioma: inglés
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• Resumen

  • In Reply:Falsification hypotheses can help adjudicate whether observational associations are robust or whether they reflect selection bias among patients who receive an intervention. Dr Groenwold thoughtfully expands on a prerequisite to proper falsification analyses: the falsification hypothesis must test a putative mechanism of bias.