Importance Active perinatal care increases survival of extremely preterm infants; however, improved survival might be associated with increased disability among survivors.
Objective To determine neurodevelopmental outcome in extremely preterm children at 2.5 years (corrected age).
Design, Setting, and Participants Population-based prospective cohort of consecutive extremely preterm infants born before 27 weeks of gestation in Sweden between 2004 and 2007. Of 707 live-born infants, 491 (69%) survived to 2.5 years. Survivors were assessed and compared with singleton control infants who were born at term and matched by sex, ethnicity, and municipality. Assessments ended in February 2010 and comparison estimates were adjusted for demographic differences.
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