Risks of In Utero Exposure to Valproate

• Autores: Kimford J. Meador, David W. Loring
• Localización: JAMA: the journal of the American Medical Association, ISSN 0098-7484, Vol. 309, Nº. 16, 2013, págs. 1730-1731
• Idioma: inglés
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• Resumen

  • Antiepileptic medications are among the most commonly prescribed teratogenic drugs among women of childbearing potential. However, determining the exact number of women of childbearing age exposed to antiepileptic medications is difficult. One estimate, based on data from the National Ambulatory Medical Care Survey and the National Hospital Ambulatory Medical Care Survey, suggests that from 2005-2007, there were 7 900 000 annual prescriptions for antiepileptic medications among girls and women aged 15 to 44 years, including 926 000 for valproate (12% of all antiepileptic medication prescriptions, irrespective of indication).