History of allergy is a predictor of adverse events in unstable angina treated with coronary angioplasty

• Autores: N.D Brunett, L. De Gennaro, A Cuculo, A. Gaglione, M. Di Biase
• Localización: Allergologia et immunopathologia: International journal for clinical and investigate allergology and clinical immunology, ISSN-e 1578-1267, ISSN 0301-0546, Vol. 41, Nº. 1, 2013, págs. 25-29
• Idioma: inglés
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• Resumen

  • Background The aim was to investigate prognostic relevance of history of allergy in subjects with unstable angina treated with coronary angioplasty.

    Methods Fifty-seven consecutive patients with unstable angina who underwent coronary angioplasty were enrolled in the study and were divided into two groups: those with a history of allergy (Group A, N=15); and controls (Group C, N=42). Major adverse cardiac events were recorded over a six-month follow-up period. Patients with primary or unsuccessful angioplasty and patients treated with drug eluting stent were excluded from the study.

    Results Group A patients (history of allergy) showed a 46.67% incidence of major adverse cardiac events at six-month follow-up (vs. 9.52% Group C, p<0.01): results remained significant even in a multiple Cox regression analysis (hazard ratio 7.17, 95% CI 1.71�29.98, p<0.01).

    Conclusion History of allergy is an independent predictor of major adverse cardiac events after coronary angioplasty in a six-month follow-up period in unstable angina.