Bone marrow transplantation for beta-thalassemia

• Autores: Claudio Giardini
• Localización: Gaceta médica de México, ISSN 0016-3813, Vol. 136, Nº. Extra 2, 2000, págs. 49-51
• Idioma: inglés
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• Resumen

  • Marrow transplantation from HLA-identical siblings has been increasingly adopted for therapy of non-malignant conditions.

    The first successful transplant in b-thalassaemia, was performed by Thomas et al. in 1981 in an untransfused 14-months old child. This patient, now aged 18 years, is the longest surviving patient who is definitely cured from a genetic disease by bone marrow transplantation. At the same time a 14-year old thalassemic patient who had recived 150 cell transfusions was transplanted in Pesaro but he had recurrence of thalassemia after rejection of the graft.