van der Woude syndrome- a syndromic form of orofacial clefting

• Autores: R. Sudhakara Reddy, T. Ramesh, N. Vijayalaxmi, R. Lavanya Reddy, L.A. Swapna, T. Rajesh Singh
• Localización: Journal of Clinical and Experimental Dentistry, ISSN-e 1989-5488, Vol. 4, Nº. 2, 2012, págs. 125-128
• Idioma: inglés
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• Resumen

  • van der Woude Syndrome is the most common form of syndromic orofacial clefting, accounting for 2% of all cases, and has the phenotype that most closely resembles the more common non-syndromic forms. The syndrome has an autosomal dominant hereditary pattern with variable expressivity and a high degree of penetrance with cardinal clinical features of lip pits with a cleft lip, cleft palate, or both.

    This case report describes van der Woude syndrome in a 19 year old male patient with a specifi c reference to the various aspects of this condition, as clinical appearance, etiological factors (genetic aspects), differential diagnosis, investigative procedures and management.