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Effect of Resistance, Endurance, and Concurrent Training on TNF-a, IL-6, and CRP

  • Autores: Cleiton Augusto Libardi, Giovana Vergínia de Souza, Claudia Regina Cavaglieri, Vera Aparecida Madruga, Mara Patrícia Traina Chacon-Mikahil
  • Localización: Medicine & Science in Sports & exercise: Official Journal of the American College of Sports Medicine, ISSN 0195-9131, Vol. 44, Nº. 1, 2012, págs. 50-56
  • Idioma: inglés
  • Texto completo no disponible (Saber más ...)
  • Resumen
    • Purpose: The aim of the present study was to evaluate the effects of 16 wk of resistance training (RT), endurance training (ET), and concurrent training (CT) on inflammatory markers, C-reactive protein (CRP), and functional capacity in sedentary middle-age men.

      Methods: Healthy subjects were randomized into RT (n = 11), ET (n = 12), CT (n = 11), and a control group (n = 13). The subjects performed three weekly sessions lasting about 60 min for 16 wk. Maximal strength was tested in bench press and leg press. The peak oxygen uptake (V?O2peak) was measured in an incremental exercise test. Plasma tumor necrosis factor-a (TNF-a), interleukin-6 (IL-6), and CRP levels were determined by an enzyme-linked immunosorbent assay.

      Results: Maximal strength was increased after 16 wk, with no differences between RT and CT. V?O2peak increased in ET and CT comparing before and after training. There were no significant differences in TNF-a, IL-6, and CRP comparing before and after training.

      Conclusions: Sixteen weeks of RT, ET, or CT in middle-age healthy men has not affected low and moderate IL-6, TNF-a, and CRP levels. CT performed in the same weekly frequency and session duration of ET and RT was effective in increasing both maximal strength and V?O2peak, in addition to improvements in lipid profile.


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