Ayuda
Ir al contenido

Dialnet


Resumen de Effect of Mental Disorders on Diagnosis, Treatment, and Survival of Older Adults with Colon Cancer

Jacques Baillargeon, Yong Fang Kuo, Yu-Li Lin, Mukaila A. Raji, Amanpal Singh, James S. Goodwin

  • OBJECTIVES: To evaluate the extent to which preexisting mental disorders influence diagnosis, treatment, and survival in older adults with colon cancer.

    DESIGN: Retrospective cohort study.

    SETTING: The Surveillance, Epidemiology and End Results (SEER)�Medicare linked database.

    PARTICIPANTS: Eighty thousand six hundred seventy participants, aged 67 and older with a diagnosis of colon cancer.

    MEASUREMENTS: The association between the presence of a preexisting mental disorder and the stage of colon cancer at diagnosis, receipt of cancer treatment, and overall and colon cancer-specific mortality were assessed using Cox proportional hazards regression and logistic regression.

    RESULTS: Participants with mental disorders were more likely to have been diagnosed with colon cancer at autopsy (4.4% vs 1.1%; P<.001) and at an unknown stage of cancer (14.6% vs 6.2%; P<.001); to have received no surgery, chemotherapy, or radiation therapy (adjusted risk ratio (ARR)=2.09, 95% confidence interval (CI)=1.86�2.35); and to have received no chemotherapy for Stage 3 cancer (ARR=1.63, 95% CI=1.49�1.79). The rate of overall mortality (hazard ratio (HR)=1.33, 95% CI=1.31�1.36) and colon cancer-specific mortality (HR=1.23, 95% CI=1.19�1.27) was substantially higher in participants with a preexisting mental disorder than in their counterparts. All of these associations were particularly pronounced in participants with psychotic disorders and those with dementia.

    CONCLUSION: Public health initiatives are needed to improve colon cancer detection and treatment in older adults with mental disorders.


Fundación Dialnet

Dialnet Plus

  • Más información sobre Dialnet Plus