Cross-Industry Standard Process for data mining is applicable to the lung cancer surgery domain, improving decision making as well as knowledge and quality management

• Autores: José Eduardo Rivo Vázquez, Javier Fuente, Ángel Rivo Vázquez, Eva García Fontán, Miguel Angel Cañizares Carretero, Pedro Gil
• Localización: Clinical & translational oncology, ISSN 1699-048X, Vol. 14, Nº. 1, 2012, págs. 73-79
• Idioma: inglés
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• Resumen

  • Objectives The aim of this study was to assess the applicability of knowledge discovery in database methodology, based upon data mining techniques, to the investigation of lung cancer surgery.

    Methods According to CRISP 1.0 methodology, a data mining (DM) project was developed on a data warehouse containing records for 501 patients operated on for lung cancer with curative intention. The modelling technique was logistic regression.

    Results The finally selected model presented the following values: sensitivity 9.68%, specificity 100%, global precision 94.02%, positive predictive value 100% and negative predictive value 93.98% for a cut-off point set at 0.5. A receiver operating characteristic (ROC) curve was constructed. The area under the curve (CI 95%) was 0.817 (0.740�0.893) (p<0.05). Statistical association with perioperative mortality was found for the following variables [odds ratio (CI 95%)]: age over 70 [2.3822 (1.0338�5.4891)], heart disease [2.4875 (1.0089�6.1334)], peripheral arterial disease [5.7705 (1.9296�17.2570)], pneumonectomy [3.6199 (1.4939�8.7715)] and length of surgery (min) [1.0067 (1.0008�1.0126)].

    Conclusions The CRISP-DM process model is very suitable for lung cancer surgery analysis, improving decision making as well as knowledge and quality management.