Muscle Metabolism during Exercise with Carbohydrate or Protein-Carbohydrate Ingestion

• Autores: Naomi M. Cermak, Amy S. Solheim, Melanie S. Gardner, Mark A. Tarnopolsky, Martin J. Gibala
• Localización: Medicine & Science in Sports & exercise: Official Journal of the American College of Sports Medicine, ISSN 0195-9131, Vol. 41, Nº. 12, 2009, págs. 2158-2164
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Dialnet Métricas: 1 Cita
• Resumen

  • Introduction: Ingesting protein (PRO) with CHO during prolonged exercise is purported to improve performance compared with CHO alone by altering the regulation of skeletal muscle energy provision. However, no study has directly investigated this issue. We tested the hypothesis that compared with CHO alone, coingestion of PRO would alter markers of metabolic control, including the magnitude of glycogen use and the net expansion of the tricarboxylic acid cycle intermediate pool, which has been linked to the capacity for oxidative energy delivery.

    Methods: Eight trained men (mean +/- SE: age = 29 +/- 2 yr; V[spacing dot above]O2peak = 55 +/- 2 mL[middle dot]kg-1[middle dot]min-1) cycled at 69% +/- 1% V[spacing dot above]O2peak for 90 min on two occasions, and biopsy samples (vastus lateralis) were obtained before and after exercise. In a randomized, double-blind manner, subjects ingested one of two drinks during exercise that contained either 6% CHO or 6% CHO + 2% PRO (CHO + PRO) at a rate of 1 L[middle dot]h-1 to deliver 60 g[middle dot]h-1 CHO +/- 20 g[middle dot]h-1 PRO.

    Results: CHO + PRO ingestion increased the plasma concentration of branched chain (561 +/- 46 vs 301 +/- 32 [mu]mol[middle dot]L-1) and essential amino acids (1071 +/- 98 vs 670 +/- 71 [mu]mol[middle dot]L-1) after exercise versus CHO (both P values <=0.05). However, net muscle glycogen use (CHO + PRO = 223 +/- 31 vs CHO = 185 +/- 38 mmol[middle dot]kg-1 dry weight) and tricarboxylic acid cycle intermediate expansion (CHO + PRO = 2.3 +/- 0.7 vs CHO = 2.1 +/- 0.2 mmol[middle dot]kg-1 dry weight) were similar between trials. Blood creatine kinase activity and 20-km time trial performance measured approximately 24 h after the first exercise bout were not different between treatments.

    Conclusion: When trained men ingest CHO at a rate on the upper end of the range generally recommended to improve endurance performance, coingestion of PRO does not alter specific markers proposed to reflect an enhanced capacity for skeletal muscle energy delivery.