Preface - Angiogenesis in development and cancer today.

• Autores: Domenico Ribatti, Valentin Djonov
• Localización: International journal of developmental biology, ISSN 0214-6282, Vol. 55, Nº. 4-5, 2011 (Ejemplar dedicado a: Angiogenesis in development & cancer), págs. 343-344
• Idioma: inglés
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• Resumen

  • The cardiovascular system plays a crucial role in vertebrate development and homeostasis. During embryonic development, vasculature is formed by both vasculogenesis and angiogenesis. Vasculogenesis, which consists of de novo vessel formation from angioblasts, provides the nascent vascular network, particularly during early embryonic life. Angiogenesis, which refers to expansion of a pre-existing vascular bed through sprouting, bridging and intussusceptive growth, intervenes mostly during later stages of embryogenesis. Recent experimental studies have demonstrated that bone-marrow-derived stem and endothelial progenitor cells can in principle contribute to tissue repair by induction of neo-angiogenesis