Glomeruloesclerosis nodular en un tabaquista hipertenso no-diabético con dislipidemia

• Autores: A. F. Predosa, W. A. Gomes, M. A. Gonçalves, F. Teles, Vitorino Modesto dos Santos
• Localización: Anales del sistema sanitario de Navarra, ISSN 1137-6627, Vol. 34, Nº. 2, 2011, págs. 301-306
• Idioma: español
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• Resumen

  • Nodular glomerulosclerosis may be idiopathic or develop associated with diabetes mellitus, membranoprolipherative glomerulonephritis, light or heavy chain deposits, amyloidosis, fibrillary or immunotactoide disease, and Takayasu�s arteritis. Histological features of idiopathic nodular glomerulosclerosis are similar to the Kimmelstiel-Wilson changes. Recent evidence points to the role of hyperglycemia, hyperlipidemia, hypertension and smoking in the mechanisms of this uncommon condition.

    The case study of a 65-year-old male presenting recent arterial hypertension and nodular non-diabetic glomerulosclerosis is described, and the possible role of heavy smoking in the pathogenesis of this condition is emphasized.