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The EORTC quality of life questionnaire for patients with colorectal cancer: EORTC QLQ-CR29 validation study for Spanish patients.

  • Autores: Juan Ignacio Arrarás Urdániz, Javier Suárez, Fernando Arias de la Vega, Ruth Vera García, Gemma Asín Felipe
  • Localización: Clinical & translational oncology, ISSN 1699-048X, Vol. 13, Nº. 1, 2011, págs. 50-56
  • Idioma: inglés
  • Texto completo no disponible (Saber más ...)
  • Resumen
    • Introduction The EORTC Quality of Life (QL) Group has developed a questionnaire -the EORTC QLQ-CR29- for evaluating QL in colorectal cancer. The aim of this study is to assess the psychometric properties of the EORTC QLQ-CR29 when applied to a sample of Spanish patients.

      Materials and methods Eighty-four locally advanced rectal cancer patients in the treatment follow-up period after receiving surgery and neoadjuvant chemoradiotherapy were included in the study. Seventy subjects also had adjuvant chemotherapy. Patients completed both the EORTC QLQ-C30 and the QLQ-CR29 once. The psychometric evaluation of the questionnaire�s structure, reliability, and convergent, divergent and known-groups validity was performed.

      Results Multitrait scaling analysis showed that three of the multi-item scales met the standards of convergent and discriminant validity. These same scales reached the 0.7 Cronbach�s coefficient criterion or were close to it. In both analyses exceptions were observed in the blood and mucus in stool scale. Correlations between the scales of the QLQ-C30 and the module were low (r<0.02) in most cases. A few areas with more related content had higher correlations (r<0.05). Group comparison analyses showed differences in QL between groups of patients based on age, comorbidity, performance status, receipt of adjuvant chemotherapy and surgery modality.

      Conclusions The EORTC QLQ-CR29 is a reliable and valid instrument when applied to a sample of Spanish rectal cancer patients. These results are in line with those of the EORTC validation study.


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