Interleukin 6 as a Key Regulator of Muscle Mass during Cachexia

• Autores: James A. Carson, Kristen A. Baltgavis
• Localización: Exercise and sport sciences reviews: a quarterly publication of the American College of Sports Medicine, ISSN 0091-6331, Vol. 38, Nº. 4, 2010, págs. 168-176
• Idioma: inglés
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• Resumen

  • Interleukin 6 (IL-6) has received significant attention for its regulatory role in muscle wasting during cachexia. This review examines the role of circulating IL-6 for decreasing muscle mass during cancer and emphasizes some of the indirect actions of IL-6 that may cause muscle wasting.