Resumen de Results of the oral egg-challenge test performed on two different groups of children: one group with a history, suggestive of allergic reaction with egg intake and the other group sensitised to hen�s egg without previous egg intake.
T. Fadeeva, J. L. Eseverri, Moisés Labrador Horrillo, T. Garriga Baraut, R.F. Ocaña Vela, S.L. Romero Conde, O. Esteso Hontoria, C. Blasco Valero, A.M. Marín Molina
Introduction Egg allergy is an adverse immune-system reaction of an IgE-mediated type, which can happen in children after egg intake and several times after their first egg intake.
Objectives Compare the results of the oral egg-challenge test in two groups of egg-sensitised children, with and without prior intake.
Patients and methods Retrospective study of two egg-sensitised groups (72 subjects).
Patients and methods Group 1: 22 children without prior egg-intake.
Patients and methods Group 2: 50 children with a clinical history of adverse reactions after egg intake.
Patients and methods Skin prick tests, egg-white specific IgE (sIgE) and yolk specific IgE, were performed on all children. The oral egg-challenge tests were performed after a period of egg-avoidance diet and when egg-white specific IgE levels were lower than 1.5KU/L.
Results 31.8% of the children in Group 1 did not tolerate egg-intake whereas 38% of the children in Group 2 did not tolerate egg-intake. Egg-avoidance periods lasted 19.5 and 18 months, respectively.
Results Egg-white specific IgE levels went down in both groups after an egg-avoidance diet. No statistically significant differences were found between the groups and the positivity of oral egg-challenge test.
Conclusions No statistically significant differences were found in the behaviour of the two groups studied.
Conclusions Given the high risk of adverse reactions, it was recommended that any egg-introduction tests were to be performed in a hospital environment on the children who were sensitised to hen�s egg (including children without prior egg intake).
