Multidisciplinary management of soft tissue sarcomas

• Autores: Angel Montero, Damián Pérez Aguilar, José Antonio López Martín
• Localización: Clinical & translational oncology, ISSN 1699-048X, Vol. 12, Nº. 8, 2010, págs. 543-553
• Idioma: inglés
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• Resumen

  • Musculoskeletal sarcomas are a heterogenous group of malignant neoplasms derived from conncetive tissue. Sarcomas represent about 1% of cancer in adults. The annual incidence in adults in Europe is around 14,000 new cases of soft tissue sarcomas (STS) and 4,800 new cases of bone sarcomas. Musculoskeletal tumours arise anywhere in the body, although lower extremities are the most common site of appearance, followed by upper extremities, trunk, retroperitoneum and head and neck area. Adequate management of STS is a stimulating challenge for oncologists. The aim of treatment should be focused on four main aspects: improving survival, avoiding local recurrence, maximising organ function and, finally, minimising morbidity. Surgery, radiotherapy and, sometimes, though increasingly, chemotherapy are the pillars on which rests the modern treatment of sarcomas. The optimal management of musculoskeletal tumour requires a multidisciplinary integration of these different approaches in treatment planning right from the initial diagnoses. Referring patients to qualified centres should be desirable to achieve the maximum probability of control and even cure for STS.