Hypoxic-ischemic encephalopathy in the term infant

• Autores: Ali Fatemi, Mary Ann Wilson, Micahel V. Johnston
• Localización: Clinics in Perinatology, ISSN 0095-5108, Vol. 36, Nº. 4, 2009 (Ejemplar dedicado a: Neurology of the Newborn Infant), págs. 835-858
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • Hypoxia-ischemia in the perinatal period is an important cause of cerebral palsy and associated disabilities in children. There has been significant research progress in hypoxic-ischemic encephalopathy over the last 2 decades, and many new molecular mechanisms have been identified. Despite all these advances, therapeutic interventions are still limited. In this article the authors discuss several molecular pathways involved in hypoxia-ischemia, and potential therapeutic targets.