Probing the fetal cardiac signal for antecedents of brain injury

• Autores: Adam J. Wolfberg, Errol R. Norwitz
• Localización: Clinics in Perinatology, ISSN 0095-5108, Vol. 36, Nº. 3, 2009 (Ejemplar dedicado a: Fetal neorology), págs. 673-684
• Idioma: inglés
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• Resumen

  • Obstetric care providers and researchers have long relied on analysis of the fetal heart rate tracing for insight into the fetal neurologic status. Although a normal fetal heart rate tracing does provide reassurance of intact neurologic function, an abnormal pattern is a very poor predictor of newborn brain injury. Indeed, if the clinical end point of interest is cerebral palsy, a non-reassuring fetal heart rate tracing has a 99% false positive rate. More recent analyses of fetal heart rate variability and fetal ECG waveforms, however, hold promise for improved diagnostic accuracy.