Novel 10 bp deletion in the translational attenuator of a constitutively expressed erm(A) gene from "Staphylococcus epidermidis"

• Autores: Leticia Millán, María Pilar Goñi Cepero, Paula Cerdá, M. Carmen Rubio, Rafael Gómez-Lus Lafita
• Localización: International microbiology: official journal of the Spanish Society for Microbiology, ISSN 1139-6709, Vol. 10, Nº. 2, 2007, págs. 147-150
• Idioma: inglés
• Enlaces
  • Texto completo (pdf)
• Resumen

  • Alterations in the erm(A) regulatory region of six clinical isolates of Staphylococcus epidermidis and one of Staphylococcus haemolyticus displaying a constitutive resistance phenotype were investigated. Anovel deletion of 10 bp with respect to the corresponding sequence of Tn554 was identified in the attenuator of a constitutively expressed erm(A) gene of one of the S. epidermidis isolates. Thus far, this is the smallest deletion conferring constitutive resistance in the translational attenuator of erm(A) in a naturally occurring S. epidermidis strain of human origin.