Function and regulation of Ena/VASP proteins

• Adam V. Kwiatkowski ^[1] ; Frank B. Gertler ^[1] ; Joseph J. Loureiro ^[1]
  1. [1] Massachusetts Institute of Technology

     Massachusetts Institute of Technology

     City of Cambridge, Estados Unidos

     
• Localización: Trends in cell biology, ISSN 0962-8924, Vol. 13, Nº 7, 2003, págs. 386-392
• Idioma: inglés
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• Resumen

  • Regulation of cytoskeletal dynamics is required to coordinate cell movement, adhesion and shape change. The Ena/VASP protein family is thought to play an important role in linking signaling pathways to remodeling of the actin cytoskeleton. This review will examine the mechanisms by which Ena/VASP function might control actin dynamics and how these proteins are linked to various signaling pathways.