Evolution by gene duplication: an update

• Autores: Jianzhi Zhang
• Localización: Trends in ecology and evolution, ISSN 0169-5347, Vol. 18, Nº 6, 2003, pág. 292
• Idioma: inglés
• Texto completo no disponible (Saber más ...)
• Resumen

  • The importance of gene duplication in supplying raw genetic material to biological evolution has been recognized since the 1930s. Recent genomic sequence data provide substantial evidence for the abundance of duplicated genes in all organisms surveyed. But how do newly duplicated genes survive and acquire novel functions, and what role does gene duplication play in the evolution of genomes and organisms? Detailed molecular characterization of individual gene families, computational analysis of genomic sequences and population genetic modeling can all be used to help us uncover the mechanisms behind the evolution by gene duplication.