Bias is ubiquitous, and medical research is no exception. Indeed, a recently published list included 45 different types of bias in medical research [ 1 ]. However, investigator bias, which we define as bias resulting from a conflict of interest arising from passionate beliefs held by the investigators, was not among them. Although rarely discussed, such a conflict requires declaration [ 2 ]. Here, we will outline how investigator bias can influence all stages of a research project.
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