Resumen de ACTN3: A Genetic Influence on Muscle Function and Athletic Performance.
Daniel G. MacArthur, Kathryn North
A common variant of the ACTN3 gene, R577X, results in complete deficiency of the [alpha]-actinin-3 protein in the fast skeletal muscle fibers of more than a billion humans worldwide. We review the evidence that this genetic variant is strongly associated with elite athlete status and with normal variation in human muscle strength and sprinting speed.
