Aerobic Run Training Improves Brachial Artery Flow-Mediated Dilation

• Autores: Joseph R. Libonati
• Localización: Journal of strength and conditioning research: the research journal of the NSCA, ISSN 1064-8011, Vol. 21, Nº. 4, 2007, págs. 1291-1295
• Idioma: inglés
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• Resumen

  • Libonati, J.R. Aerobic run training improves brachial artery flow-mediated dilation. J. Strength Cond. Res. 21(4): 1291-1295. 2007.-The purpose of this study was to assess the relationship between aerobic exercise training and brachial artery flow-mediated dilation (FMD) in healthy subjects. Healthy controls (HC) and aerobically-trained (T) subjects were studied with high-resolution vascular ultrasound at baseline, and during a 5-minute period of hyperemia following forearm cuff occlusion. Training was defined by self-reported participation in recreational or competitive run training. Forearm cuff occlusion was held at 200 mm Hg for 5 minutes. At baseline, both brachial artery flow and diameter were greater in T than in HC (p < 0.05). Resting heart rate was lower in T than in HC (p < 0.05). Peak hyperemic flow (15 seconds postocclusion) was significantly greater in T than in HC (HC; 539 ± 75 ml·min?1 vs. T; 832 ± 103 ml·min?1, p < 0.05) and correlated well with O2peak (r = 0.67, p = 0.008). Flow-mediated dilation was significantly greater in T vs. HC throughout the 5-minute postocclusion phase (p < 0.05). Maximal brachial artery dilation was greater in T than in HC (HC; 3 ± 1% of baseline vs. T; 8 ± 3% of baseline; p < 0.05) and moderately correlated with O2peak (r = 0.55, p < 0.05). These data suggest that the greater FMD observed in trained subjects may be due, in part, to an augmentation of peak hyperemic flow.